Mechanisms of Heparins / LMWHs / Fondaparinux
1. Unfractionated heparin (UFH)
- Inhibits both factor Xa and thrombin
2. Low-molecular-weight drugs
- Preferentially inhibit factor Xa (eg. enoxaparin)
3. Fondaparinux
- Inhibits factor Xa only (with antithrombin activation)
1. Unfractionated heparin (UFH)
- Inhibits both factor Xa and thrombin
2. Low-molecular-weight drugs
- Preferentially inhibit factor Xa (eg. enoxaparin)
3. Fondaparinux
- Inhibits factor Xa only (with antithrombin activation)
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