Classification
Analgesic, antipyretic, antiplatelet; nonsteroidal antiinflammatory drug (first-generation NSAID)
Action
Is a nonselective cyclooxygenase inhibitor that decreases the formation of prostaglandins involved
in the production of inflammation, pain, and fever. Inhibits platelet aggregation.
Uses
• Relieves low-to-moderate pain
• Decreases inflammation in systemic lupus erythematosus, rheumatoid arthritis,
osteoarthritis, bursitis, and tendonitis
• Is a prophylactic medication to reduce the risk of transient ischemic attack, ischemic stroke,
and myocardial infarction
Contraindications and Precautions
• Hypersensitivity to salicylates
• Do not use during pregnancy
• History of gastrointestinal (GI) ulceration, peptic ulcer disease (PUD), or any bleeding
disorder
• Use in children with a recent history of viral infection (e.g., influenza, chickenpox) has been
associated with Reye syndrome
Side Effects
• Decreases platelet aggregation; increases bleeding potential
• Epigastric distress, heartburn, and nausea
• Aspirin overdose or toxicity—respiratory alkalosis that progresses to respiratory
depression and acidosis; hyperthermia, sweating, and dehydration with electrolyte
imbalance; tinnitus, headache
Nursing Implications
1. Give with milk or full glass of water to decrease gastric irritation.
2. Teach safety measures to parents regarding medications at home.
3. The potential for toxicity is high in older adults and children.
4. Teach patient to avoid concurrent use of alcohol to decrease GI irritation.
5. Patient should not take aspirin for at least 1 week before surgery.
6. Evaluate patient to determine purpose of medication—pain, inflammation, or antiplatelet
action.
No comments:
Post a Comment